Medicine Man, created by Mr. Nice, is gaining popularity because it produces an unusually high amount of THC and other cannabinoids. The Indica effects of this hybrid are very strong, and new users are advised to be cautious. The happy high is not overwhelming, and many users feel focused, but the body numbing can bring on a very lazy effect. Negative effects usually include dry eyes and mouth, but some users may also experience paranoia or headache.

The strong sedative effects of this strain are often used to treat chronic aches and pains and migraines. For others, Medicine Man is great for reducing stress or anxiety. The strain is also prescribed to treat nausea. The extremely high amount of cannabinoids is believed to prevent seizures.

Medicine Man's genetics were first prototyped under the name White Rhino. The strain has since been perfected, and the final result is a descendant of the Widow family, crossed with a strong Afghanistan landrace Indica. It flowers for around eight weeks and has amazing yields of up to 600 grams. For the best results, this strain should be grown indoors and given a lot of care and attention.