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Cannabis and Depression

Cannabis and Depression

“No amount of sleep in the world could cure the tiredness I feel.” - Anonymous

Depression has long been a major public health issue. According to the National Institute of Mental Health, 15.7 million adults (6.7% of all U.S. adults) aged 18 or older in the United States experienced a major depressive episode in 2014. For those who suffer, depression can be a hell that has been described as “living in a body that fights to survive while your mind tries to die.”

To treat depression, doctors generally prescribe a pharmaceutical like Prozac or Zoloft. Often, they’ll also prescribe an antianxiety medication like Valium or Xanax. However, antidepressants don’t work for everyone. Worse, benzodiazepines such as Valium or Xanax can be highly addictive. Of course, we’ve all seen the commercials for these drugs. The part of the commercial devoted to listing the potential adverse side effects is usually longer than the part of the commercial describing the benefits. And, what are one of the potential side effects? Thoughts of suicide!

Clearly, the limited number of effective options to treat depression are, in fact, depressing! No wonder many people choose to self-medicate with cannabis to treat depression. However, how does cannabis play into the equation? There has long been an association between depression and cannabis consumption. But, it’s been a chicken and the egg thing. Does cannabis consumption cause depression, or do people with depression use cannabis to to alleviate their depression?

While all important considerations, first, let’s start by defining “depression.”

What is Clinical Depression?

While everyone experiences periods where they “feel depressed,” at what point is it depression? Feeling sad or blue after experiencing a common life event — such as a job loss or the break up of a relationship — is a normal human response. But, what actually constitutes clinically diagnosable depression?

According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) — the “bible” used by mental health professionals in the U.S. to diagnose mental health conditions — major depressive disorder is defined as experiencing either depressed mood or loss of interest or pleasure over a period of two weeks or longer, and at least five out of nine identified symptoms that reflect a change in functioning, such as problems with sleep, diet, energy, feelings of self-worth, and concentration.

What Causes Depression?

It’s important differentiate between “risk factors,” “triggers,” and “causes.” They’re all closely related and often used interchangeably, but there are subtle, notable, distinctions.

Risk factors - Natural or environmental factors that increase one’s likelihood of developing depression. For example, heredity can be a natural risk factor, as mental illness is known to run in the family. Substance abuse, on the other hand, is an example of an environmental risk factor. For example, it’s well established that alcoholism is a major risk factor in developing depression.

Trigger - A causal event that triggers the onset of a depressive episode. For example, a death in the family, job loss, emotional abuse, disease, or even taking a medication, as some medications are known to trigger depression.

Causes - In this context, what is the physiological explanation for depression? For example, a chemical imbalance (i.e. a serotonin deficiency).

Contrary to popular belief, we can’t point to a single factor — like serotonin deficiency — that causes depression. It’s likely the interaction of several factors, such as stressful life events, medical issues, genetic vulnerability and physiological functions that work together to elicit the onset of a depressive episode.

Further, evidence suggests there are multiple pathways that could be factors in causing major depression, including faulty mood regulation by the brain, chronic inflammatory response and alterations of the endocannabinoid system. Of course, ingestion of cannabinoids affect endocannabinoid system (ECS), and the ECS plays an important role in modulating the body’s inflammatory response. Which, of course, makes the study of cannabis and depression even more interesting. Could cannabis provide the key to unlocking a class of new therapeutic options to treat depression? Quite possibly.

Australian psychiatry researchers from the University of Newcastle upon Tyne write: “Anandamide, tetrahydrocannabinol (THC) and cannabidiol (CBD) variously combine antidepressant, antipsychotic, anxiolytic, analgesic, anticonvulsant actions, suggesting a therapeutic potential [for cannabinoids] in mood and related disorders.”

The Endocannabinoid System: Its Role In Mood & Well-Being

Our body’s own cannabinoid system — the endocannabinoid system (ECS) — is one of the most important physiological systems in our bodies, as it plays an indispensible role in helping us maintain physical and emotional health. The ECS does far more than just modulate the psychoactive effects of cannabis — it plays a major role in appetite, pain sensitivity, memory, and of course, mood and well-being.  

There are numerous paths to manipulate the endocannabinoid system. When you ingest cannabis, you’re also ingesting THC and CBD (along with dozens of other plant cannabinoids). These cannabinoids then bind to receptors in the ECS to elicit pharmacological effects beyond just getting you “high,” or creating euphoria. (This is why cannabis can be medicine or an inebriant.)

Interestingly, exercise can stimulate production of the body’s naturally occurring version of THC, the “bliss molecule,” anandamide. You’ve no doubt heard about the “runner’s high.” Well, it’s likely anandamide molecules (not endorphins) cause this high. Chocolate lovers take note — dark chocolate also stimulates anandamide production.

As researchers have noted, the endocannabinoid system is involved in mood and related disorders. Clearly, modifying the ECS through activities like exercise is beneficial in regulating mood. Likewise, consuming synthetic and plant-based cannabinoids modify the ECS. Obviously, many people use cannabis because it makes them “feel good.” What’s less clear is to what degree the short-term benefits translate into potential long-term benefits or adverse effects.

Here’s what we know so far...

How Does Cannabis Affect Depression?

Dr. Ethan Russo, one of the most important figures in cannabis medicine, notes that in India, cannabis was credited for helping alleviate anxiety and depression as far back as 1500 B.C.E. In recent history, the Ohio State Medical Committee on Cannabis stated in 1860: "As a calmative and hypnotic, in all forms of nervous inquietude and cerebral excitement, it will be found an invaluable agent, as it produces none of those functional derangement or sequences that render many of the more customary remedies objectionable.”

It’s a truism, to proclaim that a great many people use cannabis because it makes them “feel good.” Because it makes them “happy,” and it elevates their mood. There’s nothing particularly controversial about those statements. However, what has been a source of controversy during recent years is what the relationship is between cannabis and depression. It’s only been quite recently that among mainstream scientific community has there been an interest in studying cannabis and cannabinoids for its potential therapeutic value in treating psychiatric conditions such as depression.

As part of the perpetual, seemingly unending, “War on Drugs,” research funding has been allocated disproportionately to prove cannabis is a dangerous drug that warrants residency in perpetuity on the DEA’s infamous Schedule I — reserved for the world’s most dangerous and addictive drugs. Consequently, despite the fact throughout recorded history cannabis has been credited for its antidepressive powers, there are very few high-quality, scientifically rigorous studies that exist demonstrating cannabis’s potential as an antidepressant. As the public’s perception of cannabis continues to rapidly evolve over recent years, and the scientific community follows, more research is now being done. But, we’re still in our infancy.

Irrespective, of federal policy that has impeded serious scientific study of whole-plant cannabis for decades, we’ve managed to accumulate some notable research no less.

Here’s what the research tells us so far:

The Effects (Good and Bad) of THC Are Dose-Dependent

One thing that is well-established is that THC produces dose-dependent biphasic effects. What the heck does that mean? Low to moderate effects elicit desirable effects; too high of doses, produce the exact opposite effects. This should be pretty obvious to anyone who has ingested too much of an edible, or smoked too much. You can get paranoid or anxious. Quite simply: moderate doses of THC tend to produce pleasant effects like euphoria and relaxation, while too high of doses could exacerbate anxiety or depression — at least acutely. The science is still out on the long-term effects of chronic consumption.  

Again, we don’t have much “gold standard” research studies on humans, but preclinical research — on lab rats and mice — tend to support this hypothesis. Anecdotal reports from her patients inspired Dr. Gabriella Gobbi — and her team at McGill University — to embark on a study to evaluate the potential of cannabis to act as an antidepressant.

"As a psychiatrist, I noticed that several of my patients suffering from depression used to smoke cannabis. And in the scientific literature, we had some evidence that people treated with cannabis for multiple sclerosis or AIDS showed a big improvement in mood disorders. But there were no laboratory studies demonstrating the antidepressant mechanism of action of cannabis."

Gobbi and her team conducted their research on experimental animal models by injecting the mice with a synthetic version of THC. What they found is that in low doses, the synthetic version of THC had a potent antidepressant effect, significantly increasing serotonin in the rats' brains. However, at higher doses the exact opposite occurred: serotonin levels dropped significantly. She noted, also, that “excessive cannabis use in people with depression poses high risk of psychosis.” However, since this study, research has emerged to suggest THC only increases the risk of psychosis in individuals who are predisposed to it.

Notably, Gobbi’s research only tested synthetic isolated THC. We now know that CBD —  the (largely) non-psychoactive sibling of THC — is a potent force of temperance against THC. CBD — proportional to its concentration — offsets most potential adverse effects of THC.

CBD Produces Antidepressant (And Antianxiety) Effects

Remarkably, our appreciation for CBD’s huge therapeutic potential is a recent phenomenon — it’s only really taken off over the last five years. Within psychiatric research, preclinical studies in humans and animals have found that not only could CBD potentially treat depression and anxiety, it alleviates withdrawal effects from drugs like opioids. (In fact, it can even reduce cue-driven drug-seeking behaviors and cravings.)

CBD is the most popular (largely) non-psychoactive cannabinoid found in cannabis. Researchers (and others) frequently point to CBD as having tremendous potential to treat  psychiatric conditions, noting, also, that among its antidepressant and antianxiety potential, it can counteract potential adverse effects of THC. (In fact, it could quite possibly also be a powerful antipsychotic agent.)

Other studies, too, suggest CBD has powerful antidepressant and antianxiety properties.

Spanish researchers, conducting (another) experimental study using animal models (e.g. mice), found that by enhancing serotonin and glutamate levels, CBD could be a fast-acting antidepressant drug.  

Another study conducted by researchers in Israel and Brazil noted that in human trials, CBD doses producing the most impressive results were nominally high (well, not that high!), however, they identified three other CBD derivatives that could be incredibly potent antianxiety and antidepressant agents at very low doses.

Cannabis Use (Probably) Doesn’t Cause Depression

Clearly, our scientific understanding of cannabis and ongoing research are pointing to expanding therapeutic roles of cannabis (particularly CBD) to elevate mood and alleviate depression, but what about all the talk over the years that cannabis use can actually cause depression? Well, that research has been largely debunked.

Swedish researchers conducted a study of 8598 Swedish men and women between the ages of 20 and 64 over a three year period. After factoring in other risk factors such as alcohol and illicit drug use, adverse life events, family tension, they found no statistically significant data to suggest that cannabis use triggers depression.

In January 2015, researchers published a longitudinal study in Journal of Affective Disorders releasing findings from data they analyzed that was collected by the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) and concluded that cannabis use was not significantly associated with an increase in major depressive episodes.

Depression May Lead People to Use More Cannabis

But, of course, all the news can’t be good. While cannabis may not cause depression —  users generally perceive cannabis as helping them alleviate depressive symptoms — there is strong evidence that already depressed individuals are at an elevated risk to increase their cannabis consumption to potentially problematic levels. Moreover, there’s a risk that depression could increase anxiety levels and accelerate transition in vulnerable individuals from casual to problematic use.

Keep in mind, however, that in studies there were generally overlapping factors beyond depression that lead to problematic use — such as a parent who had a history of mental illness or drug use disorder.

A 2014 study showed that depression or “pre-existing anxiety was associated with higher average levels of cannabis intoxication, which in turn was linked to acute anxiety responses due to cannabis use." Further, researchers have found depressive episodes were “associated with increased speed of transition to dependence, which is consistent with emerging findings of an association between depression and cannabis use disorders.”

Interestingly, the perception of getting better or higher quality sleep may be one of the reasons people increase cannabis use. A study published in The American Journal of Drug and Alcohol Abuse suggests that “individuals with heightened depression may have higher rates of problematic cannabis use, in part, because of the beneficial effects of cannabis in terms of perceived sleep quality.” According to one of the study’s researchers, Marcel O. Bonn-Miller, “Sleep issues are often a problem in people who are depressed, and many individuals will use cannabis to help them sleep. Paradoxically, while the individual may solve one problem — in this case, sleep — they may creating a bigger long-term problem. Dependency.”  

Cannabis (Laws) Reduce Suicide Rates

On another positive note, cannabis — or at least the enactment of medical marijuana laws — is saving lives! In the seminal paper, High on Life? Medical Marijuana Laws and Suicide, researchers reported that after states enact medical marijuana laws they experience a nearly 5 percent reduction in total suicide rate. And, it gets better! Among 20 to 29 year old males, the suicide rate declines by 11%, while 9% fewer 30 to 39 year old males commit suicide.

While this data provides compelling evidence for liberalizing cannabis laws, it doesn’t necessarily speak to the antidepressant powers of cannabis. There could be other factors contributing to the reduction in suicides:

First off, adverse life events which cause a shock in individuals who were otherwise happy can cause someone to commit suicide. Medical marijuana laws remove criminal penalties for qualified patients using, possessing or cultivating cannabis. While these penalties apply to medical marijuana patients, and few states allow patients to obtain a recommendation for mental health issues, most states allow patients to use marijuana to treat subjectively measured conditions like chronic pain and nausea.

Individuals often obtain a cannabis recommendation to treat chronic pain, when in fact, they are obtaining it for other reasons. By not having to risk arrest, they are no longer subjected to potential criminal penalties that could cause a whole host of issues that are known to cause significant stress. Beyond legal issues, following an arrest, individuals often face other stressors, such as the loss of employment, child custody, or a relationship.

Another interesting possible explanation is that because alcohol consumption goes down in medical marijuana states, so does suicide. There is a clear association between alcohol use and suicide. Alcoholism is associated with an increase in suicidal ideation and completed suicides.

While this research may not provide insights into the potential therapeutic benefits, it incontrovertibly demonstrates that liberalization of marijuana laws reduces suicides, and that is obviously a wonderful thing!

At the end of the day, depression is a complex condition, and cannabis is a highly complex plant with more than a hundred cannabinoids. We’re only just beginning to develop an understanding of how cannabis and cannabinoids could play a role in treating depression. Thus far, research is still in its infancy. Again, because most research has been confined to find negative associations between cannabis use and mood disorders, studies demonstrating how cannabis plays a role in psychiatric disorders are limited, but offer encouragement.

The data so far suggests cannabis research — from a sociopolitical and therapeutic perspective — should be a priority.  However, as long as the federal government continues to consider cannabis a Schedule I drug — meaning they believe it’s highly addictive and there are no accepted medical uses — scientists have to navigate numerous bureaucratic obstacles to conduct much needed research. Nonetheless, the research is clear that there is a direct link between the enactment of medical marijuana laws and a reduction in suicides. The fact that suicide claims three times as many lives as homicides in the U.S. every year and cannabis could reduce this rate, provides a compelling argument to continue dismantling cannabis prohibition and ending the failed “War on Drugs.” 

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Starbud
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Indica - THC 20%
Strawberry Cough
(4)
Sativa - THC 23%
Super Silver Haze
(3)
Sativa - THC 23%
Titanium
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Hybrid - THC 22%
Top 44
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Indica - THC 20%
X-Kush #1
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Indica - THC 21%
Albert Walker
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Indica - THC 15%
Anunnaki
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Sativa - THC 19%
Cannalope Haze
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Sativa - THC 20%
Chernobyl
(5)
Sativa - THC 30%
Chocolate Haze
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Sativa - THC 17%
Chocolate Thai
(2)
Sativa - THC 10%
Cole Train
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Indica - THC 19%
Destroyer
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Sativa - THC 23%
F.O.G.
(1)
Sativa - THC 21%
Flying Dragon
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Hybrid - THC 18%
Golden Tiger
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Sativa - THC 24%
Jack's Cleaner
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Sativa - THC 17%
La Blanca
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Indica - THC 15%
Lowryder
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Sativa - THC 14%
Rug Burn OG
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Indica - THC 26%
Sonoma Coma
(1)
Sativa - THC 25%
Super Lemon Haze
(4)
Sativa - THC 25%
The Black
(1)
Indica - THC 18%
Arjan's Haze
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Sativa - THC 22%
Cannatonic
(2)
Hybrid - THC 6%
Crimea Blue
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Indica - THC 18%
Flowerbomb Kush
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Sativa - THC 19%
Holy Grail Kush
(2)
Indica - THC 24%
M-39
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Hybrid - THC 14%
Madness
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Hybrid - THC 18%
Mazar
(1)
Indica - THC 20%
Motavation
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Indica - THC 18%
Pineapple Punch
Leave a review
Sativa - THC 15%
Purple Haze
(1)
Sativa - THC 20%
Durban Poison
(5)
Sativa - THC 26%
Deadhead OG
(1)
Sativa - THC 25%
Tangerine Dream
(2)
Sativa - THC 25%
Sweet Tooth
Leave a review
Indica - THC 19%
Bruce Banner
(5)
Sativa - THC 30%
Death Star
(3)
Indica - THC 26%
Flo
(2)
Sativa - THC 14%
Jean Guy
Leave a review
Sativa - THC 25%
Mars OG
Leave a review
Indica - THC 20%
Obama Kush
(1)
Indica - THC 21%
Trinity
(4)
Sativa - THC 20%
Ghost Train Haze
(1)
Sativa - THC 25%
Cannalope Kush
(1)
Sativa - THC 22%
Gigabud
(1)
Indica - THC 19%
$100 OG Kush
(1)
Hybrid - THC 25%
Super Sour Diesel
Leave a review
Sativa - THC 26%
Hash Plant
(2)
Indica - THC 13%
Cinex
(1)
Sativa - THC 26%
Sour Kush
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Indica - THC 26%
Blue Diesel
(2)
Indica - THC 23%
A-10
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Indica - THC 24%
Afwreck
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Sativa - THC 26%
Blue Dragon
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Indica - THC 24%
Chemdawg 4
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Indica - THC 28%
Great White Shark
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Indica - THC 24%
J1
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Sativa - THC 23%
King Louis XIII
(1)
Indica - THC 28%
Strawberry Diesel
Leave a review
Hybrid - THC 27%
Yoda OG
(3)
Indica - THC 22%
Golden Goat
(3)
Sativa - THC 23%
God Bud
(1)
Indica - THC 27%
Candyland
(1)
Sativa - THC 19%
Purple Urkle
(1)
Indica - THC 26%
Tangerine Man
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Sativa - THC 18%
Raspberry Cookies
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Indica - THC 26%
Raspberry Kush
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Indica - THC 17%
Thin Mint Cookies
(2)
Hybrid - THC 24%
Purple Widow
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Indica - THC 22%
Hurricane
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Sativa - THC 18%
Snow Ryder
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Indica - THC 23%
Purple Trainwreck
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Hybrid - THC 26%
Super Skunk
(1)
Indica - THC 28%
Purple Headband
Leave a review
Indica - THC 28%
Sour OG
(4)
Hybrid - THC 27%
Lemon OG
(1)
Indica - THC 24%
Animal Cookies
(3)
Indica - THC 27%
Candy Jack
(1)
Sativa - THC 27%
Stardawg
(2)
Sativa - THC 22%
Grape Stomper
(1)
Sativa - THC 22%
Critical Jack
(1)
Sativa - THC 20%
Khalifa Kush
(3)
Indica - THC 29%
White Fire OG
(3)
Indica - THC 25%
Bubba's Gift
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Indica - THC 20%
Green Goblin
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Sativa - THC 24%
Purple Arrow
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Indica - THC 24%
Zombie OG
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Indica - THC 21%
Golden Pineapple
Leave a review
Hybrid - THC 29%
ACDC
(1)
Hybrid - THC 6%
Tres Dawg
(1)
Hybrid - THC 25%
Sour Jack
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Hybrid - THC 22%
Purple Rhino
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Indica - THC 20%
Rainbow Kush
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Indica - THC 17%
Sour Tsunami
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Sativa - THC 10%
Goji OG
(1)
Hybrid - THC 22%
Plushberry
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Hybrid - THC 20%
Cherry AK-47
Leave a review
Sativa - THC 21%
Blue Champagne
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Sativa - THC 25%
Gorilla Glue #4
(11)
Sativa - THC 32%
Green Ribbon
(1)
Hybrid - THC 28%
Purple Elephant
Leave a review
Hybrid - THC 25%
Chemdawg Sour Diesel
Leave a review
Sativa - THC 26%
Tangie
(1)
Sativa - THC 22%
Blueberry
(4)
Indica - THC 24%
Afghani
(1)
Indica - THC 21%
Triangle Kush
(1)
Indica - THC 26%
Tahoe Alien
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Indica - THC 29%
Alien Kush
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Indica - THC 19%
Snow White
(1)
Indica - THC 22%
Purple Jems
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Hybrid - THC 19%
Alien Technology
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Indica - THC 19%
White Nightmare
(2)
Sativa - THC 22%
White Moonshine
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Indica - THC 19%
Larry OG
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Indica - THC 24%
Hawaiian Haze
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Sativa - THC 26%
Hawaiian
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Sativa - THC 25%
West Coast Diesel
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Sativa - THC 26%
Twilight
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Indica - THC 21%
Khufu
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Indica - THC 27%
Blue Moonshine
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Indica - THC 16%
Black Cherry Soda
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Hybrid - THC 30%
Big Skunk Korean
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Hybrid - THC 19%
Purple Power
(1)
Sativa - THC 20%
Jamaican
(1)
Sativa - THC 21%
Purple Princess
(1)
Indica - THC 17%
Ice Queen
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Sativa - THC 23%
Oriental Express
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Sativa - THC 16%
SAGE
(1)
Sativa - THC 25%
Las Vegas Purple Kush
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Indica - THC 23%
Chemdawg 91
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Hybrid - THC 24%
Critical Plus
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Hybrid - THC 20%
The White
(2)
Sativa - THC 30%
Snow Lotus
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Indica - THC 25%
Chem's Sister
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Sativa - THC 28%
California Orange
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Hybrid - THC 15%
Arcata Trainwreck
(1)
Sativa - THC 26%
Chocolate Hashberry
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Hybrid - THC 25%
Thai
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Sativa - THC 22%
Lost Coast OG
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Indica - THC 15%
MK Ultra
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Indica - THC 22%
Blue God
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Indica - THC 20%
Blue Cookies
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Indica - THC 25%
Blackwater
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Indica - THC 20%
Bay Dream
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Sativa - THC 26%
Alien OG
(2)
Sativa - THC 28%
Cookies and Cream
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Hybrid - THC 25%
Double Dream
(1)
Sativa - THC 26%
Dr. Who
(1)
Hybrid - THC 30%
Gelato
(1)
Hybrid - THC 25%
Glass Slipper
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Sativa - THC 25%
Key Lime Pie
(1)
Hybrid - THC 25%
Jet Fuel
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Sativa - THC 20%
Orange Cookies
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Indica - THC 20%
Mob Boss
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Hybrid - THC 21%
Alpha Blue
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Sativa - THC 20%
Cali Kush
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Indica - THC 15%
C4
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Indica - THC 22%
Bordello
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Indica - THC 20%
Blueberry Pie
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Hybrid - THC 20%
Blue Hawaiian
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Hybrid - THC 24%
Apple Kush
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Indica - THC 20%
Candy Cane
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Indica - THC 20%
Grape God
(1)
Indica - THC 25%
Jesus OG
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Hybrid - THC 28%
Cornbread
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Indica - THC 20%
Conspiracy Kush
(1)
Indica - THC 25%
Royal Kush
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Indica - THC 25%
Grape Royale
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Indica - THC 28%
Kimbo Kush
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Indica - THC 27%
Professor Chaos
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Sativa - THC 25%
Dirty Girl
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Sativa - THC 28%
Wedding Cake
(3)
Indica - THC 25%
Emerald Jack
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Sativa - THC 20%
Cotton Candy Kush
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Indica - THC 20%
Blueberry Cheesecake
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Sativa - THC 20%
Blue Kush
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Hybrid - THC 18%
Aspen OG
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Sativa - THC 20%
Blue Ivy
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Indica - THC 20%
Blue Haze
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Indica - THC 26%
Isla OG
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Hybrid - THC 27%
Boss Hogg
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Indica - THC 20%
Oracle
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Hybrid - THC 14%
Big Wreck
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Indica - THC 27%
Bay 11
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Sativa - THC 25%
White Buffalo
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Sativa - THC 25%
Sunshine Daydream
(1)
Indica - THC 25%
Strawberry Banana
(1)
Indica - THC 26%
Sour Grape
Leave a review
Hybrid - THC 24%
Purple Dragon
Leave a review
Sativa - THC 20%
Snoop's Dream
(1)
Hybrid - THC 25%
Presidential OG
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Indica - THC 26%
P-91
Leave a review
Hybrid - THC 20%
Sunset Sherbet
(1)
Indica - THC 24%
Blue Mango
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Indica - THC 18%
Golden Ticket
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Hybrid - THC 26%
Allen Wrench
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Sativa - THC 28%
Dutch Berry
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Sativa - THC 27%
Cherries Jubilee
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Indica - THC 22%
Lemon Wreck
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Sativa - THC 20%
Panda OG
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Sativa - THC 25%
Middlefork
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Sativa - THC 26%
Dutch Hawaiian
Leave a review
Sativa - THC 28%
Lodi Dodi
(1)
Sativa - THC 28%
Head Cheese
(1)
Hybrid - THC 30%
Tiger's Milk
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Hybrid - THC 17%
Malawi
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Sativa - THC 24%
Laughing Buddha
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Sativa - THC 20%
Frank's Gift
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Sativa - THC 9%
Headbanger
(1)
Sativa - THC 28%
Dream Star
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Indica - THC 25%
Citrix
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Sativa - THC 23%
Clementine
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Sativa - THC 27%
Fruit Loops
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Indica - THC 19%
Deep Purple
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Indica - THC 19%
Cherry Cookies
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Hybrid - THC 26%
Banana OG
(1)
Indica - THC 25%
Hell's Angel OG
Leave a review
Indica - THC 20%
XXX OG
(1)
Indica - THC 21%
Cherry Pie
(1)
Indica - THC 26%
Rare Darkness
(1)
Indica - THC 26%
Starfighter
Leave a review
Indica - THC 26%
Blue Magoo
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Indica - THC 21%
Liberty Haze
(1)
Hybrid - THC 29%
Cheesequake
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Indica - THC 22%
Blue Boy
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Sativa - THC 27%
Blue Diamond
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Indica - THC 24%
Blue Dot
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Sativa - THC 20%
Blue Frost
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Indica - THC 22%
Blue Goo
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Hybrid - THC 22%
Cannasutra
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Indica - THC 23%
Gucci OG
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Hybrid - THC 30%
Stephen Hawking Kush
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Indica - THC 12%
Paris OG
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Indica - THC 28%
Blowfish
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Indica - THC 26%
Blackberry Pie
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Hybrid - THC 19%
Black Russian
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Indica - THC 26%
Black Mamba
(1)
Sativa - THC 25%
Black Ice
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Indica - THC 24%
Black Haze
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Sativa - THC 22%
Black Diamond
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Indica - THC 24%
Alien Rock Candy
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Indica - THC 18%
Narnia
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Sativa - THC 25%
Pink Champagne
Leave a review
Indica - THC 23%
Pink Panties
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Indica - THC 24%
Emerald OG
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Indica - THC 22%
Appalachia
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Hybrid - THC 21%
Pink Death Star
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Indica - THC 23%
Godzilla
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Indica - THC 18%
Sour Patch Kiss
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Sativa - THC 31%
Grease Monkey
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Hybrid - THC 30%
Blueberry Blast
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Indica - THC 28%
Blue Venom
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Indica - THC 23%
Blue Thai
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Hybrid - THC 21%
Blue OG
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Indica - THC 19%
Blue Nightmare
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Hybrid - THC 19%
Blue Jay Way
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Hybrid - THC 8%
Blue Knight
(1)
Hybrid - THC 27%
Blue Magic
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Hybrid - THC 23%
Blue Power
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Indica - THC 27%
Blue Sky
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Indica - THC 19%
9 Pound Hammer
(2)
Indica - THC 23%
Huckleberry
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Hybrid - THC 26%
Cookie Monster
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Indica - THC 23%
Chronic
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Sativa - THC 20%
Bubba OG
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Indica - THC 27%
Berry Bomb
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Indica - THC 23%
Afgoo
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Indica - THC 28%
Blurple
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Hybrid - THC 19%
Abusive OG
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Indica - THC 32%
Hawaiian Punch
(1)
Sativa - THC 25%
Cherry Skunk
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Indica - THC 22%
Cherry OG
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Hybrid - THC 23%
Charlie Sheen
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Sativa - THC 24%
Tutti Frutti
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Hybrid - THC 23%
Willy Wonka
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Sativa - THC 28%
24K Gold
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Indica - THC 24%
3x Crazy
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Hybrid - THC 23%
Bubbleberry
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Sativa - THC 21%
Sour Moonrocks
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Sativa - THC 59%
Syrup OG
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Indica - THC 30%
Alpha Omega OG
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Sativa - 70%
Harambe's Ghost
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Hybrid - THC 30%
Cheese Candy
(1)
Sativa - THC 20%
Chocolate Kush
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Indica - THC 28%
Cookie Dough
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Hybrid - THC 25%
Diamond OG
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Indica - THC 22%
Frankenstein
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Indica - THC 29%
Euphoria
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Indica - THC 6%
Euforia
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Sativa - THC 23%
Gobbstopper
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Hybrid - THC 21%
Tesla Tower
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Sativa - THC 22%
Fruit Punch
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Sativa - THC 25%
Incredible Hulk
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Sativa - THC 24%
King Kong
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Indica - THC 21%
Orange Creamsicle
(1)
Sativa - THC 18%
Dairy Queen
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Hybrid - THC 28%
Deep Sleep
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Indica - THC 20%
Dizzy OG
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Hybrid - THC 22%
K2
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Indica - THC 29%
Lucky Charms
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Hybrid - THC 22%
Pez
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Indica - THC 27%
THC Bomb
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Hybrid - THC 26%
Jager
(1)
Indica - THC 23%
Lucid Dream
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Sativa - THC 28%
Memory Loss
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Sativa - THC 28%
Pitbull
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Indica - THC 21%
CBD Kush
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Indica - THC 8%
Somango
(1)
Indica - THC 23%
Sexxpot
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Indica - THC 15%
LA Woman
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Hybrid - THC 28%
Transformer
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Hybrid - THC 22%
Lemon Cake
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Sativa - THC 25%
Blueberry Diesel
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Indica - THC 23%
Blueberry Haze
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Sativa - THC 23%
Blueberry Headband
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Hybrid - THC 18%
Chocolate Chunk
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Indica - THC 22%
Green Goddess
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Indica - THC 20%
Hippie Crippler
(1)
Hybrid - THC 27%
Jedi Kush
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Indica - THC 30%
Kona Gold
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Sativa - THC 15%
Silver Surfer
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Hybrid - THC 26%
Lemon Haze
(1)
Sativa - THC 25%
Citrus Sap
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Sativa - THC 24%
Colombian Gold
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Sativa - THC 20%
Deep Chunk
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Indica - THC 20%
Dog Shit
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Sativa - THC 26%
Early Girl
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Indica - THC 20%
Game Changer
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Indica - THC 29%
LA OG
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Hybrid - THC 24%
Lemon Drop
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Sativa - THC 23%
Cabbage Patch
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Hybrid - THC 27%
Earth OG
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Indica - THC 22%
Exodus Cheese
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Hybrid - THC 18%
Goo
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Indica - THC 24%
Killing Fields
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Sativa - THC 22%
Locomotion
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Indica - THC 23%
Mammoth
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Hybrid - THC 21%
Mexican
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Sativa - THC 16%
Milky Way
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Sativa - THC 22%
Blueberry Yum Yum
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Sativa - THC 25%
Haole
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Indica - THC 17%
Hog
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Indica - THC 23%
Ingrid
(1)
Indica - THC 25%
Killer Queen
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Hybrid - THC 21%
Kong
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Hybrid - THC 20%
Lifesaver
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Hybrid - THC 21%
Love Potion #1
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Sativa - THC 18%
Atomic Northern Lights
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Indica - THC 24%
Watermelon
(1)
Indica - THC 22%
White Girl
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Sativa - THC 30%
Pie Face
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Indica - THC 19%
Royal Dutch
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Hybrid - THC 21%
Recon
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Indica - THC 23%
Remedy
(1)
Indica - THC 1%
Shark's Breath
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Indica - THC 26%
Shoreline
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Sativa - THC 23%
Sugar Plum
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Sativa - THC 26%
Sunshine
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Sativa - THC 27%
Sweet Dream
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Sativa - THC 23%
Do Si Do
(1)
Hybrid - THC 30%
True OG
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Hybrid - THC 24%
Venom OG
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Hybrid - THC 27%
Acid
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Indica - THC 23%
Afghan Cow
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Sativa - THC 22%
Alaska
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Sativa - THC 31%
Aloha
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Sativa - THC 24%
Armageddon
(1)
Sativa - THC 20%
Butter OG
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Indica - THC 24%
Cali Gold
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Indica - THC 21%
U.K. Cheese
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Hybrid - THC 18%
Gorilla Glue #1
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Hybrid - THC 28%
ICED Grapefruit
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Sativa - THC 24%
Julius Caesar
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Hybrid - THC 20%
Mother’s Milk
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Sativa - THC 16%
Medicine Woman
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Sativa - THC 24%
Money Maker
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Indica - THC 23%
Moonshine Haze
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Sativa - THC 25%
Omega
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Hybrid - THC 26%
Orange Juice
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Indica - THC 15%
Orange Kush
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Hybrid - THC 24%
Orange Velvet
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Hybrid - THC 22%
Oregon Diesel
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Indica - THC 22%
Pineapple Jack
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Hybrid - THC 20%
Raspberry Cough
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Sativa - THC 24%
Red Diesel
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Hybrid - THC 22%
Silver Pearl
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Sativa - THC 21%
Skunkberry
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Hybrid - THC 40%
Skywalker OG
(1)
Indica - THC 26%
Sour Apple
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Indica - THC 27%
Sour Bubble
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Indica - THC 28%
Sour Cookies
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Sativa - THC 28%
Bubblegum Kush
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Indica - THC 23%
Chocolate Diesel
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Sativa - THC 18%
Grape Cookies
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Indica - THC 24%
Grape Crush
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Indica - THC 19%
Green Candy
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Hybrid - THC 24%
Green Dragon
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Indica - THC 16%
Green Dream
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Hybrid - THC 24%
Green Love Potion
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Indica - THC 24%
Incredible Bulk
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Indica - THC 24%
LA Chocolat
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Indica - THC 29%
Pineapple Thai
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Sativa - THC 24%
Pink Lemonade
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Indica - THC 22%
Platinum Kush
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Indica - THC 17%
Power Kush
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Hybrid - THC 19%
Pure Kush
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Indica - THC 24%
Purple Berry
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Indica - THC 22%
Purple Bud
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Indica - THC 20%
Purple Candy
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Hybrid - THC 19%
Purple Champagne
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Sativa - THC 29%
Purple Cheese
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Hybrid - THC 22%
Sour Dream
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Sativa - THC 21%
Sour Power
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Sativa - THC 29%
Space Cream
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Indica - THC 24%
Strawberry Blue
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Sativa - THC 20%
Strawberry Cheesecake
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Indica - THC 22%
Strawberry Dream
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Hybrid - THC 21%
Strawberry Ice
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Sativa - THC 21%
Strawberry Kush
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Sativa - THC 23%
Strawberry
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Hybrid - THC 18%
Sugar Mama
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Hybrid - THC 19%
White Berry
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Indica - THC 22%
White Cheese
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Hybrid - THC 16%
White Dream
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Hybrid - THC 24%
White Elephant
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Hybrid - THC 23%
White Gold
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Indica - THC 25%
White Lightening
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Hybrid - THC 24%
Afghan Haze
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Sativa - THC 21%
Agent Tangie
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Sativa - THC 18%
Super Blue Dream
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Hybrid - THC 21%
Super Cheese
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Indica - THC 25%
Super Jack
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Sativa - THC 24%
Suzy Q
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Hybrid - THC 1%
Sweet Black Angel
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Indica - THC 18%
Tangerine Haze
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Sativa - THC 21%
Tangerine Kush
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Indica - THC 20%
Walter White
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Sativa - THC 21%
The Sauce
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Sativa - THC 28%
Tangerine Power
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Sativa - THC 25%
Arabian Gold
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Hybrid - THC 22%
Godfather OG
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Indica - THC 28%
Lemon G
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Sativa - THC 23%
Lemon Thai
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Hybrid - THC 22%
Mango
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Hybrid - THC 24%
Locktite
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Indica - THC 23%
Mango Tango
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Indica - THC 26%
Pink Kush
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Indica - THC 22%
Master Yoda
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Hybrid - THC 28%
Alien Bubba
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Indica - THC 21%
Aurora Indica
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Indica - THC 20%
Azure Haze
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Indica - THC 20%
Banana Candy
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Indica - THC 24%
Barbara Bud
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Indica - THC 19%
BC Big Bud
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Sativa - THC 21%
BC Roadkill
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Indica - THC 25%
Belladonna
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Sativa - THC 26%
Birds Eye
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Hybrid - THC 25%
Black Bubba
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Indica - THC 24%
Mega Jackpot
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Sativa - THC 25%
Maui
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Sativa - THC 26%
Purple Crack
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Sativa - THC 19%
Purple Cream
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Hybrid - THC 24%
Purple Dream
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Hybrid - THC 15%
test strain
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Sativa - THC 4%
test strain 1
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Indica - 0%
Tangerine
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Hybrid - THC 18%
The Flav
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Indica - THC 24%
Black Velvet
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Hybrid - THC 20%
Blackberry Cream
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Indica - THC 25%
Blackberry Haze
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Sativa - THC 24%
Blackberry Trainwreck
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Hybrid - THC 20%
Oaxacan Highland
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Sativa - THC 23%
Puna Budder
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Hybrid - THC 22%
strain11
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Indica - THC 1%
Martian Candy
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Indica - THC 21%
Medusa
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Hybrid - THC 20%
Monkey Paw
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Indica - THC 23%
Wappa
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Indica - THC 22%
Greek Kalamata
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Sativa - 0%
Purple Goo
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Hybrid - THC 21%
Purple Gorilla
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Indica - THC 21%
Purple Nepal
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Indica - THC 25%
Night Train
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Hybrid - THC 23%
Purple Passion
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Indica - THC 18%
Purple Skunk
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Sativa - THC 20%
Purple Star
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Indica - THC 13%
Purple Thai
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Sativa - THC 24%
Purple Voodoo
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Hybrid - THC 16%
White Lotus
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Hybrid - THC 22%
White Queen
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Indica - THC 25%
White Siberian
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Indica - THC 15%
White Slipper
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Sativa - 70%
Blue Lights
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Indica - THC 16%
Jack's Girl
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Hybrid - THC 54%
Purple Wreck
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Indica - THC 31%
Blue Monster
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Indica - THC 23%
Blue Satellite
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Hybrid - THC 22%
Blue Train
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Hybrid - THC 20%
Blueberry Jack
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Hybrid - THC 20%
Buddha Haze
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Sativa - THC 26%
Cambodian
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Sativa - THC 26%
Caramelo
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Sativa - THC 31%
Chiquita Banana
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Hybrid - THC 34%
Chocolate Fondue
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Sativa - THC 17%
Colorado Chem
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Hybrid - THC 22%
Cookie Jar
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Indica - THC 24%
Critical Haze
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Hybrid - THC 21%
Crosswalker
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Indica - THC 22%
Death Bubba
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Indica - THC 27%
Deep Cheese
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Indica - 80%
Double Diesel
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Sativa - THC 22%
Double Dutch
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Sativa - THC 18%
Double OG
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Indica - THC 26%
Dreamer's Glass
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Sativa - THC 22%
Early Pearl
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Sativa - THC 24%
Earthquake
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Hybrid - THC 23%
Dream Lotus
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Hybrid - THC 21%
Red Poison
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Hybrid - THC 21%
Easy Bud
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Sativa - THC 17%
Enigma
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Sativa - THC 24%
Red Cherry Berry
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Hybrid - THC 22%
Ether
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Indica - THC 21%
Ray Charles
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Indica - THC 21%
G.O.A.T.
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Sativa - THC 19%
Raw Diesel
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Hybrid - THC 19%
Rafael
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Sativa - THC 2%
Grape Skunk
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Indica - THC 24%
Grapefruit Haze
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Hybrid - THC 25%
Green Hornet
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Hybrid - THC 20%
Green Kush
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Hybrid - THC 24%
Green Poison
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Indica - THC 20%
Hawaiian Delight
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Hybrid - THC 20%
Quebec Gold
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Hybrid - THC 26%
Hawaiian Skunk
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Indica - THC 17%
Himalayan Gold
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Indica - THC 25%
Pure Power
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Sativa - THC 26%
Hindu Skunk
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Indica - THC 23%
Hippie Chicken
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Sativa - THC 23%
Hollywood OG
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Hybrid - THC 20%
Silver Kush
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Sativa - THC 24%
Holy Ghost
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Hybrid - THC 28%
Honey Boo Boo
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Indica - THC 21%
Humboldt
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Hybrid - THC 25%
Jack Diesel
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Sativa - THC 23%
Jack Haze
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Hybrid - THC 22%
Silver Bubble
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Hybrid - THC 20%
Jacky White
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Sativa - THC 18%
Jamaican Lion
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Hybrid - THC 18%
Jenni
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Sativa - THC 11%
Jimi Hendrix
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Hybrid - THC 17%
Shaman
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Sativa - THC 18%
Juicy Jack
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Hybrid - THC 25%
Juliet
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Sativa - THC 20%
Serious 6
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Hybrid - THC 17%
Seattle Blue
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Hybrid - THC 20%
Sapphire Star
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Hybrid - THC 24%
Santa Maria
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Sativa - THC 14%
Rubicon
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Hybrid - THC 9%
K1
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Sativa - THC 16%
King's Bread
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Sativa - THC 21%
LA Kush
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Indica - THC 21%
Royal Highness
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Sativa - THC 15%
Rene
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Sativa - THC 18%
Lime Green Skunk
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Hybrid - THC 17%
Liquid Butter
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Indica - THC 20%
Loud Scout
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Indica - THC 23%
Project Blue Book
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Hybrid - THC 22%
Magnum
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Hybrid - THC 15%
Mango Dream
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Hybrid - THC 23%
Master Bubba
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Hybrid - THC 8%
Master Jedi
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Hybrid - THC 25%
Pink Pez
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Hybrid - THC 23%
Pineapple Skunk
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Indica - THC 27%
Master Skunk
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Hybrid - THC 19%
Melon Gum
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Indica - THC 23%
Jamaican Dream
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Sativa - THC 21%
Pineapple Haze
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Sativa - THC 22%
Molokai Frost
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Sativa - THC 70%
Monster OG
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Indica - THC 26%
Morning Star
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Sativa - THC 24%
Mother of Berries
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Indica - THC 24%
Ms Universe
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Hybrid - THC 24%
Mt Cook
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Indica - THC 23%
Mt Rainier
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Hybrid - THC 23%
Neptune OG
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Hybrid - THC 23%
Nova
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Indica - THC 23%
NYPD
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Sativa - THC 24%
Odyssey
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Hybrid - THC 22%
OG Skunk
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Sativa - THC 26%
Old Toby
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Indica - THC 18%
Orange Diesel
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Sativa - THC 16%
Orange Haze
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Sativa - THC 20%
Orange Skunk
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Sativa - THC 16%
Orange Turbo
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Sativa - THC 15%
Ortega
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Indica - THC 17%
Pineapple Diesel
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Hybrid - THC 18%
Purple People Eater
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Indica - THC 23%
Purple Sour Diesel
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Sativa - THC 21%
Skunk 47
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Indica - THC 27%
Sour Bubba
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Sativa - THC 31%
Sour Haze
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Sativa - THC 26%
Sour Maui
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Sativa - THC 27%
Star Berry
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Indica - THC 20%
Stevie Wonder
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Sativa - THC 24%
Strawberry Lemonade
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Hybrid - THC 28%