Nukeheads is an aptly named hybrid strain that can lean either Indica or Sativa depending on which phenotype presents itself, and the quality of the harvest and cure. Nukeheads is also the namesake strain created by cannabis company Nukeheads, which is headed by famous grower Cody Oebel. The team keeps this strain's genetic history a secret, a good move for a proprietary namesake strain like this one. The primary reason consumers and growers are infatuated with this strain is the presence of polyploid flowers, which increase the yield and provides for a unique experience. Nukeheads' ideal consumption time is based on its effects, as sativa-leaning Nukeheads are great for the daytime, while Indica Nukeheads are better saved for the evening.

Nukeheads the plant is quite the sight to behold. It can grow up to fifteen feet tall due to its powerful hybrid genetics in addition to its tendency to grow incredibly thick and supportive stalks. Some growers have measured stalks two-inches thick for plants just under two feet in height, which is definitely overkill for a plant that size. A good way to spot which phenotype is presenting is by looking at the leaves on the plant as it grows. Wide, fat leaves are typical of its Indica phenotype, while thinner leaves are a sign that the Sativa phenotype is presenting. These oversized buds are unique in that they are polyploid, meaning they form as double-headed. It’s this rare genetic anomaly that has made Cody Oebel and his team so fond of the strain, and they market it as a truly unique "must-try" experience for just about everyone.

The effects coupled with the strain's incredibly high THC concentration of 27% make for a uniquely powerful strain that even Nukeheads the growers themselves warn users of on their website. They suggest taking it slow with until you're comfortable with its sedative effects, at which point the strain becomes a powerful energetic smoke. Nukeheads' high is a powerful cerebral high that will have you not only flexing your mental muscles but smiling from ear to ear. This euphoric boost in mood is just what many need to help fight symptoms of depression and anxiety. The later effects are sure to make you incredibly sleepy and sedated while at the same time pretty hungry, so do yourself a favor and prepare a tasty snack before taking a hit. Many who pick this strain up consistently do so with the intention of relieving symptoms of insomnia, pain, depression, headaches, and anxiety. A number of reviews from medical cannabis patients suggest that Nukeheads is a valuable tool in restoring the lack of appetite and fighting nausea caused by chemotherapy.