Michigan Skunk, originally bred in the southeastern part of Michigan, is a mainly Indica strain specifically intended for pain relief. Its mother is a three-way cross of a strain with unknown heritage named God, a landrace Hawaiian Sativa, and Shaman from Dutch Passion. It was bred with a male Skunk #1 and a Hindu Kush hybrid. Michigan Skunk produces a powerful body buzz that can last up to four hours. During the first hour, patients may feel as if they are floating. The effect is relaxing, and in the following hours, many feel very drowsy.

Suitable for a multitude of ailments, Michigan Skunk may lessen even the worst of chronic aches and pains. It is also useful in inducing appetite, calming nausea, and relieving insomnia. Thanks to its mellow high, it may be recommended to those suffering from paranoia and anxiety, especially the sort that can lead to panic attacks. 

The strain can reach up to four feet in height and reportedly can produce over 200 grams per plant after a flowering period of 8 to 10 weeks. Exceptionally easy to care for, the strain can be successfully grown by growers of any experience level. Michigan Skunk can be grown inside, where it produces higher THC levels, or outside for a larger yield. Plants of this strain can give off a powerful skunk aroma. Due to the plant's large root system, those that prefer hydro should use deep water cultivation. When grown outside, the plant should be topped four times and pruned every six days.