Hollands Hope is an extremely sturdy Indica-dominant hybrid. It flourishes in varying conditions outdoors (both hot and cool, humid and arid) and is relatively mold resistant. Its name comes from its ability to grow well outdoors during Holland's unpredictable summer climate, bringing hope to farmers.

The strain's high begins with uplifting cerebral effects, making users feel giggly and happy. These effects are followed by a strong muscle-relaxing buzz that can envelope the whole body. Higher doses may produce couch-lock, sedation, increased appetite, and sleep. Negative side effects include dry eyes and mouth. Some users report paranoia, dizziness, and anxiety (especially when the strain is taken in higher doses).

This strain can be very effective for pain management, easing aches and knots in muscles. Hollands Hope is prescribed for the relief of stress, anxiety, and mood disorders such as chronic depression. It can also stimulate appetite and calm nausea. Sometimes, it is used to stave off cachexia, a syndrome of severe weight loss that can accompany cancer.

Hollands Hope is descended from Afghanistan (Indica) and Skunk (Sativa). Positronics developed this strain specifically to survive the wet summers in Holland. Other breeders have selectively bred or crossed the strain to release their own versions of Hollands Hope. The strain should be grown outdoors as it can reach heights of over 180 cm. It is highly resistant to mold and pests. It flowers between eight and nine weeks. Typical yields reach as much as 700 grams per plant.