You may have heard of vitamin B4 as a cure-all for everything from hangovers to digestion. The strain B4 is similarly therapeutic, with the added benefit of a well-balanced psychoactive high. Created by breeders MTG Seeds, who have also given us Orange Creamsicle, B4 is a cross between the uber-popular Blue Dream and potent Chemdawg 4. The THC content of these colorful and fragrant buds has been measured at between 15% and 26%.

Flowers of B4 are characterized by a medium to large size and a tapered, almost cylindrical shape. The buds adhere in a structure that appears characteristically sativa, with fluffy-looking leaves that spiral loosely outward from their central stems. The leaves themselves are a yellowish green and are wound through with rust-colored pistils. Finally, translucent white trichomes give these flowers a dewy look when seen from afar, and account for their high psychoactivity.

On initial inspection, B4 carries the unmistakable blueberry flavor of parent strain Blue Dream Hanging out underneath is a spicy, peppery kick. Grinding up these buds, meanwhile, yields some skunkiness along with a hit of astringent chemical odor that may be passed on from Chemdawg. When combusted in a pipe or a joint, B4 burns with a very smooth and pleasant smoke. This smoke tastes like a mixture of berries and skunk on the exhale.

B4 doesn’t take very long after ingestion to begin working its magic. Shortly after toking, users may feel an increased blood pressure around the temples and lower forehead, along with a possible increase in salivation. These strange sensations are accompanied by an uptick in higher-level thinking. Thoughts can take on a cerebral quality, with a sudden focus on concept that might not otherwise seem interesting. This mental activity makes B4 a good way to execute complex, work-related tasks, as well as more creative, open-ended projects like brainstorming. Alternatively, the strain’s buzzy energy may help make boring tasks like laundry slightly more interesting. As time passes, B4’s indica side tends to emerge, sending progressive waves of relaxation rolling down the spine. Within an hour or so, consumers may notice that they’re able to breathe more deeply and easily and may feel relief from any tight knots of muscular tension. While its may not knock users out entirely, the sedation can be enough to sap the motivation to power through active pursuits. In these later stages, B4 might be better suited to lounging with some spacey music or a compelling binge-watching session. In whatever context you use it, though, the strain may be especially fun when shared with a group of mellow, like-minded friends, as it can facilitate giggles and free-flowing conversation. Because of its slow dip in animation and energy, B4 is recommended for consumption starting in the late afternoon; if used as a wake-and-bake strain, it’s more likely to make you crash by late morning.

B4’s versatile also gives it several applications for medical cannabis patients. The sense of focus associated with this high’s onset may boost concentration for those with attention deficit disorders. Its upbeat, energetic vibe can also have a temporarily soothing effect on the harsh symptoms of stress and depression. B4 can also relieve physical pain, whether it’s due to a chronic disease like lupus or arthritis, or simply temporary inflammation like headaches or nausea. Because its patterns of recursive, cerebral thinking can veer into paranoia in the wrong circumstances, B4 is not recommended for patients who are prone to panic or who have a low THC tolerance.

Seeds of B4 are not available (or at least not regularly stocked) for sale online. Those looking to grow the strain at home should obtain clippings from mature plants in order to foster identical “clones.” B4 can be grown indoors or outdoors in a semi-humid, Mediterranean-like climate. It flowers within 8 to 9 weeks when grown indoors and offers gardeners a relatively high yield of buds at harvest time.

B4’s wide-ranging effects make it a great all-purpose smoke. The strain’s high resin content also makes it useful for creative homemade hash and other concentrates.