Sensi Seeds created American Dream not only because of the analogy between growing cannabis and the flowering of the dreams of America's forefathers but also because of a comment made by one of the strain's developers. The comment was toward breeders who work with specific plants over long periods of time and who hope each generation would be more successful than the previous one. Sensi Seeds believed they achieved this ideal by mixing the genetics of an Afghanistan Indica, Skunk #1, a Jamaican Sativa, and a Hawaiian Sativa. American Dream is Indica dominant but provides a subtle cerebral effect with a calming body high. Because it is not overpowering, American Dream is useful for daytime pain relief.

While capable of growing in sub-tropical climate outdoors, American Dream is most often grown indoors or in a greenhouse. Thanks to a large central cola and modest lateral branching, it is ideal for the Sea of Green method. Sensi Star says this strain needs 40 to 45 days to finish flowering. Once it does, the third reason behind the strain's name becomes obvious. When in full bloom, the strain is a perfect representation of life, liberty and the pursuit of happiness.